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  • Milbemycin oxime + spinosad is a heartworm disease preventive that also controls hookworms, roundworms, whipworms, and fleas in dogs. Milbemycin oxime + spinosad is given by mouth as a flavored chew tablet. At prescribed doses, this medication is well-tolerated. Your veterinarian will advise you on the safety of this product’s use in your dog. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

  • Silymarin is an over-the-counter nutritional supplement that is used off-label and is given by mouth to treat liver and cancer conditions. Give as directed. Side effects are uncommon but may include vomiting or diarrhea. Do not use it in pets that are allergic to it. If a negative reaction occurs, please call the veterinary office.

  • Mirtazapine is given by mouth or is applied to the skin and is used to treat weight loss in cats and is used off-label to treat inappetence, nausea, and vomiting in cats and dogs. Give as directed. The most common side effects include vocalization, restlessness, vomiting, incoordination, or trembling. Do not use it in pets that are allergic to it or that have recently used an MAOI. If a negative reaction occurs, call your veterinarian.

  • Miscarriage refers to the death of a fetus during pregnancy, with the most common cause being bacterial infection. Hormonal shifts or abnormalities may also cause miscarriages. In many cases, there are no visible signs of miscarriage. If miscarriage is suspected, ultrasound is used to assess the pregnancy and determine whether the fetuses are alive. Finding a cause for the miscarriage, especially if that cause is a treatable condition, may improve outcomes in future pregnancies.

  • Mitral valve disease is often one of the earliest indicators of heart disease that could lead to heart failure. It is more common in small dogs than large breeds. This handout discusses mitral valve disease in dogs, a degeneration of the valve between the left atrium and left ventricle. The clinical signs, diagnosis, treatment, and the prognosis of this condition are outlined.

  • Pets that have been diagnosed with epilepsy are usually prescribed one or more medications to prevent convulsions or seizures. Careful monitoring of epileptic pets is necessary, not only to make sure the dose of the medicine is right, but also to ensure there are no problems related to the long-term use of the medication. The most important thing to do is follow your veterinarian's instructions closely and give the medication regularly and consistently. This will ensure that the value reported on the blood test is reliable.

  • Most dogs seem to take moving in stride, if they are with are with their familiar social group. Try to anticipate changes in the dog’s routine and introduce the changes prior to the move. Familiarize your dog with any novel noises that might be associated with the new home. If there will be new pets or people in the new home, arrange introductions ahead of time in a neutral location. When you arrive at your new home, give your dog plenty of time to adjust before trying to leave him alone.

  • Moxidectin is an avermectin antiparasitic that is used to prevent heartworms and treat intestinal parasites. Imidacloprid treats and prevents fleas. These two drugs are combined in one topical product for use in cats, dogs, and ferrets. Use as directed. Side effects are uncommon and usually short-lived, however, if you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

  • Moxidectin + sarolaner + pyrantel is a heartworm disease preventive for dogs that also treats and prevents internal parasites (hookworms and roundworms) and kills fleas and ticks. This medication is given by mouth as a flavored chew tablet. At regular doses, this medication is well-tolerated. Your veterinarian will advise you on the safety of moxidectin + sarolaner + pyrantel use in your dog. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

  • Pain research has advanced suggesting that a more appropriate choice for managing the chronic pain of OA is multi-modal therapy. Non-steroidal anti-inflammatory drugs are just one of the options leveraged for multi-modal OA management. These include joint supplements, nutraceuticals, nutrition, adjunctive medicines, physical medicine, and changes to the home environment. Every multi-modal treatment plan is tailored to meet the needs of the individual patient and then adjusted as treatment progresses. Once a full multi-modal pain management plan is in place, your veterinarian may be able to lower the dose of NSAID to minimize the risk of an adverse event, and to reserve a full therapeutic dose for any acute inflammatory pain event.